to hold on for dear life, to seize an opportunity
Precisamos agarrar essa chance com unhas e dentes!
We need to seize this chance with everything we've got!
The expression agarrar com unhas e dentes ("to grab with nails and teeth") evokes the image of clinging to something so fiercely that you defend it with every part of your body, refusing to let go.
Source: Priberam.
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