Meaning
To hit on someone / To make a move
Example
Ele vive dando em cima da nova vizinha.
He keeps hitting on the new neighbor.
Origin
The phrase's origin is uncertain. A commonly-cited interpretation is direct: to 'hit on someone from above' = to approach them with an unmistakable romantic advance.
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More idioms
Acertar na moscaTo guess correctly / To hit the nail on the headAmigo da onçaA fake/false friendAndar na linhaTo toe the line / To behave properlyArmar um barracoTo cause a public sceneRodar a baianaTo cause a public scene / To go ballisticArrumar sarna pra se coçarTo ask for troubleArrastar as asasTo hit on someone / To flirtAbrir o jogoTo come clean / To open upArregaçar as mangasTo roll up one's sleeves / To get to workAgarrar com unhas e dentesTo hold on for dear life / To seize an opportunity