to lose the thread, to lose one's train of thought
Fui interrompido tantas vezes que perdi o fio da meada.
I was interrupted so many times that I lost my train of thought.
Aulete documents perder o fio da meada for losing the sequence or continuity of an idea or account; literally, a meada is a skein of thread.
Source: Aulete — fio; Aulete — meada.
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