快速答案
canto 指空间内部的角落；esquina 指街道交汇的街角。
可靠的方法是先判断这个词在句子里的功能，再翻译。
每个词的作用
canto
corner or side
Use canto for an interior corner, a tucked-away place, or one side of a space.
esquina
street corner
Use esquina for the place where streets meet.
如何选择
- canto: Choose canto if the sentence points to an interior corner, a tucked-away place, or one side of a space.
- esquina: Choose esquina if the sentence points to the place where streets meet.
例句
A cadeira está no canto da sala.
The chair is in the corner of the room.
A farmácia fica na esquina.
The pharmacy is on the corner.
常见误区
Canto also means singing in another context. The street-corner meaning still normally requires esquina.
放到语境中练习
从你的真实生活中选一个句子，写两遍：一次用 canto，一次用 esquina。如果两个版本都可以，说明意思怎样变化。