Meaning
To get down to business / To roll up one's sleeves
Example
Chega de planejamento, vamos pôr a mão na massa!
Enough planning, let's get down to business!
Origin
'Pôr a mão na massa' (put the hand in the dough) — baking or bread-making imagery. You can't mix dough with gloves on; you have to get your hands in it.
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More idioms
Acertar na moscaTo guess correctly / To hit the nail on the headAmigo da onçaA fake/false friendAndar na linhaTo toe the line / To behave properlyArmar um barracoTo cause a public sceneRodar a baianaTo cause a public scene / To go ballisticArrumar sarna pra se coçarTo ask for troubleArrastar as asasTo hit on someone / To flirtAbrir o jogoTo come clean / To open upArregaçar as mangasTo roll up one's sleeves / To get to workAgarrar com unhas e dentesTo hold on for dear life / To seize an opportunity